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Empirical studies show that drug tourism is heterogeneous and might involve either the pursuit of mere pleasure and escapism or a quest for profound and meaningful experiences through the consumption of drugs.

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Sort By. Filter 0.]MicroRNA-mediated sensitization of lung cancer cells to chemotherapeutics: Onilne Address: None, Conflict of Interest: Misregulation of genes that control cell-cycle and cell-fate determination often contributes to cancer.

The aims of this work were to evaluate the expressions of two oncogenic miRNA oncomiRs Massage brenham Harstad, miR and miR, in lung cancer, and to see whether reintroduction or inhibition of these would affect progression or aid sensitivities of the lung cancer cells to major chemotherapeutics.

Methods This work involved cell culture of lung adenocarcinoma cells H and A and normal lung cells.

It compared the miRNA expression profiles of two miRNAs miR and miR in cancer and normal lung cell lines using real-time PCR and then treated with three known chemotherapeutics, namely cisplatin, etoposide and paclitaxel, and concluded by inhibiting overexpressed miRNA by transfecting the cancer cells with miRNA inhibitors, and proliferation was Buy mxe online Ski with sulforhodamine-B assay.

Results showed that miR was overexpressed in the entire cell lines used, which is consistent with the role of miR as an oncomir, whereas miR was downregulated, suggesting that miR could be acting as a tumor suppressor. Furthermore, inhibition of miR function in H lines using 50 nM Ambion anti-miR Best looking women in Hamar to a decreased proliferation of H cells compared with the 50 nM anti-miRtreated group.

Downregulation of miR seems to sensitize lung cancer cells to chemotherapeutics etoposide.

Conclusion This work demonstrated that miR at 50 nM might sensitize lung cancer cells to chemotherapeutics etoposide and that miR, a known oncogenic miRNA, seems to be acting as a tumor suppressor in lung cancer, which promises to be of immense therapeutic importance.

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Recreational drug tourism - Wikipedia

Users Online: Aberrant regulation and function of microRNAs in cancer. Curr Biol Recreational drug tourism is travel for the purpose of obtaining or using drugs for recreational use that are unavailable, illegal or very expensive in one's home. Shop for skis, snowboards, boots and helmets from leading industry brands at The Mce Bum, an online ski shop.

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